Thanks to your support, we have made great progress on our studies into our ability to monitor and manage severe asthma using new telemonitoring technologies. With our new lung function test, which probes the lungs using gentle sound waves while the patient breathes normally into the telemonitoring device, we are able to gain insightful information about the mechanics of the lungs. In particular, we have been able to show how lung function exhibit day-to-day variations, that become greater just before a flareup. Excitingly, we seem to be able to pick up these changes in lung mechanics days before the patient is even aware of their symptoms.
We are currently working on taking advantage of these patterns to design and optimise computer algorithms, which will hopefully help us predict when a flareup is about to occur. Your support enables us to enlist talented and enthusiastic data scientists to develop these algorithms. At present we are able to achieve accuracies up to 80% in predicting flareups within a week – a great deal better than any predictor we have available, while allowing for timely intervention.
This work will form a critical part of an alert system we hope to devise, which detects upcoming flareups and sends an alarm to the patient or doctor when an intervention is needed. Our next step will be to test this alert system in a larger clinical trial. We aim to eventually incorporate this alert system into future telemonitoring devices, so that it can be used widely to help patients avoid hospital or emergency visits, perhaps even prevent flareups from occurring in the first place.
We are so grateful for your support and we look forward to updating you on our progress.
Professor Greg King & Cindy King